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Image Search Results
Journal: PLoS ONE
Article Title: Quantitative Analysis of Focused A-To-I RNA Editing Sites by Ultra-High-Throughput Sequencing in Psychiatric Disorders
doi: 10.1371/journal.pone.0043227
Figure Lengend Snippet: A . Shows the distribution of A-to-I RNA editing frequency of 36 sites from category I, including 11 of the ‘new’ sites identified by Li et al (ref 24) and 25 previously ‘known’ sites, in the cortex and cerebellum from two sets of normal human brain samples. The RNA editing frequency is presented as a percentage of the total population of transcripts. A two-fold increase of RNA editing frequency at 6 sites (CCNI (R/G), CCNI (K/R), 5HT2C (siteB), 5HT2C (siteC), 5HT2C (siteE) and TRO) in cortex and one site (FLNB) in cerebellum are shown in the inset. B . Shows the distribution of A-to-I RNA editing frequency of 36 sites from category I, in the anterior temporal cortex (ATC) and the right frontal cortex (RFC) from the third set of normal human samples (n = 5). The RNA editing frequency is presented as a percentage of the total population of transcripts. No significant difference was found between these two regions of cortex.
Article Snippet: Human cortex and
Techniques:
Journal: Brain and behavior
Article Title: The behavioral and physiological effects of high-fat diet and alcohol consumption: Sex differences in C57BL6/J mice.
doi: 10.1002/brb3.708
Figure Lengend Snippet: FIGURE 6 Whole-brain BDNF. When normalized to their respective sex controls, males overall exhibited small but significant decreases to BDNF compared to females. Black bars indicate water, and gray bars indicate 10% EtOH. The dashed line indicates 100% RC H2O expression. ‡ significant sex difference at p < .05
Article Snippet: A low target concentration (working dilution 1:2) of sample and sample diluent buffer was created and then used in a BDNF ELISA (
Techniques: Expressing